Introduction The computerized Cancer Registry at SKMCH & RC is a data system
designed for collection, management, and analysis of detailed data on
patients registered at the Hospital. The Cancer Registry at the Hospital
has been functioning since the inauguration of the Hospital in December
1994. Every year the Registry generates cancer statistics according to
sex, age, demographic area, topography, morphology, stage, grade etc.
From December 1994 till December 2003, the International Classification
of Diseases, Ninth Revision, Clinical Modification, was used to code the
diseases. On January 2004, the Registry implemented the International
Classification of Disease for Oncology, Third Edition (ICD-O-3) to code
the cancer cases. |
Results
During the last sixteen years, a total of 48,434 neoplasms were
registered at SKMCH & RC (of which 2072 were benign and 46,362
malignant). The distributions seen amongst males and females were
(49.29% and 50.71%, respectively). About 88.55% tumors were found in
adults whereas 11.45% were diagnosed in children. The top three
malignancies in all age group and both sexes combined were breast
cancer, leukemia, and lip & oral cavity cancer. The top three
malignancies amongst adult females were: cancers of the breast, ovary
& uterine adnexa, and lip & oral cavity, whereas, in adult
males, they were lip & oral cavity, liver & intrahepatic bile
ducts and non-Hodgkin’s lymphoma.
In adults, regardless of
gender, malignant neoplasm of the breast, lip & oral cavity, and
liver and intrahepatic bile ducts, were established as the leading
malignancies, whereas, in children, the commonest malignancies were
categorized as acute lymphoblastic leukemia (ALL), Hodgkin’s disease,
and non-Hodgkin’s lymphoma (NHL). In the year 2010, a total of
4,107 malignancies were added to the Registry database. Of a total of
4,107 malignant cases, 3,824 (93.11%) were analytical cases, whereas 283
(6.89%) were non analytical cases (Class of case 0 to 2 and 3 to 9 are
considered analytical cases and non-analytical cases respectively
according to the Facility Oncology Revised Data Standards (FORDS)
Revised for 2004). The top three malignancies in all age groups and both
sexes combined were breast, liver & intrahepatic bile ducts, and
lip & oral cavity cancers. In adult males, liver & intrahepatic
bile ducts, lip & oral cavity, and colorectal were the top
malignancies whereas in adult females, breast, lip & oral cavity and
liver & intrahepatic bile ducts were the leading malignancies. In
children, Hodgkin’s lymphoma, acute lymphoblastic leukemia and
non-Hodgkin’s lymphoma were the commonest malignancies. The
Registry uses the American Joint Committee on Cancer (AJCC) staging
manual for staging all available cancer sites. TNM categorizes cancers
in stages 0, 1, 2, 3, 4, and also as unstageable. Amongst 3,824
analytical cases (Class of case 0, 1, 2) , 0.58% cases were staged into
stage 0, 12.44% in stage I, 21.56% in stage II, 23.80% in stage III, and
17.29% in stage IV. In 16.55% of the patients, no AJCC stage was
defined and 7.79% of the cases were unstageable.
Histological
grading was done in 3,824 analytical cases. According to the histology
grade, 7.53% presented in Grade I, 22.86% in Grade II, 23.54% in Grade
III, 1.54% in Grade IV, and in 44.53% Grade was not determined.
The details of these reports/documents can be viewed by using the following links:
Collective Cancer Registry Report (1994-2010) (PDF file) Annual Cancer Registry Report (2010) (PDF file) CRCDM – Confidentiality - June, 2011 (PDF file)
Archived Cancer Registry Reports (Adobe Acrobat Reader is required to view the reports.) Contact:
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Suggested Citation
-Cancer Registry and Clinical Data Management (CRCDM) – Shaukat Khanum
Memorial Cancer Hospital and Research Center (SKMCH & RC) -
(www.shaukatkhanum.org.pk). Report based on cancer cases registered at
SKMCH & RC from Dec. 1994-Dec. 2010 and in 2010. Released June,
2011. |