CANCER REGISTRY AND CLINICAL DATA MANAGEMENTIntroduction The computerized Cancer Registry at SKMCH & RC is a data system designed for collection, management, and analysis of detailed data on patients registered at the Hospital. The Cancer Registry at the Hospital has been functioning since the inauguration of the Hospital in December 1994. Every year the Registry generates cancer statistics according to sex, age, demographic area, topography, morphology, stage, grade etc. From December 1994 till December 2003, the International Classification of Diseases, Ninth Revision, Clinical Modification, was used to code the diseases.
|  | On January 2004, the Registry implemented the International
Classification of Disease for Oncology, Third Edition (ICD-O-3) to code
the cancer cases.
Results
During the last Fourteen years, a total of 39,949 neoplasm cases were registered at SKMCH & RC (of which 1,499 were benign and 38,450 malignant). The distributions seen amongst males and females were (49.12% and 50.88%, respectively). About 88.56% tumors were found in adults whereas 11.44% were diagnosed in children. The top three malignancies in all age group and both sexes combined were breast cancer, leukemia and non-Hodgkin’s lymphoma (NHL). The top three malignancies amongst adult females were: cancer of the breast, ovary & uterine adnexa, and lip & oral cavity, whereas, in adult males, they were non-Hodgkin’s lymphoma, lip & oral cavity, and liver and intrahepatic bile ducts.
In adults, regardless of gender, malignant neoplasm of the breast, lip & oral cavity, and non-Hodgkin’s lymphoma, were established as the leading malignancies, whereas, in children, the commonest malignancies were categorized as acute lymphoblastic leukemia (ALL), Hodgkin’s disease, and non-Hodgkin’s lymphoma (NHL).
In the year 2008, a total of 4,182 malignancies were added to the Registry database. Of a total of 4,182 malignant cases, 3,613 (86.39%) were analytical cases, whereas 569 (13.61%) were non analytical cases. The top three malignancies in all age group and both sexes combined were breast cancer, Liver & intrahepatic bile ducts and lip & oral cavity cancer. In adult males, liver, lip & oral cavity and prostate were the top malignancies whereas in adult females, breast, Ovary and colorectal were the leading malignancies. In children, ALL, Hodgkin’s lymphoma, and NHL were the commonest malignancies.
The Registry uses the American Joint Committee on Cancer (AJCC) staging manual for staging all available cancer sites. TNM categorizes cancers in stages 0, 1, 2, 3, 4, and also as unstageable. Amongst 3,613 analytical cases (Class of case 0,1,2) , 0.83% cases were staged into stage 0, 11.51% in stage I, 24.74% in stage II, 24.30% in stage III, and 17.52% in stage IV. In 10.32% of the patients, no AJCC stage was defined and 10.80% of the cases were unstageable.
In histological grading, 6.80% presented in Grade I, 25.46 % in Grade II, 25.66% in Grade III, 1.68% in Grade IV, and in 40.41% Grade was not determined.
The details of these reports can be viewed by using the following links:
Collective Cancer registry report (1994-2008) (PDF file)
Annual Cancer Registry Report (2008) (PDF file)
Archived Cancer Registry Reports
(Adobe Acrobat Reader is required to view the reports.)
Suggested Citation - Cancer Registry and Clinical Data Management (CRCDM) -
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, Shaukat Khanum Memorial Cancer Hospital and Research Center (SKMCH & RC) - (www.shaukatkhanum.org.pk). Report based on cancer cases registered at SKMCH & RC from December 1994 to December 2008 and in 2008. Released June, 2009. |
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