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CANCER REGISTRY AND CLINICAL DATA MANAGEMENT

 PUNJAB CANCER REGISTRY – REPORT 1


Cancer Registry and Clinical Data Management
Shaukat Khanum Memorial Cancer Hospital Registry
                                                                                                                       
 

Introduction                                           

The computerized Cancer Registry at SKMCH & RC is a data system designed for collection, management, and analysis of detailed data on patients registered at the Hospital. The Cancer Registry at the Hospital has been functioning since the inauguration of the Hospital in December 1994. Every year the Registry generates cancer statistics according to sex, age, demographic area, topography, morphology, stage, grade etc. From December 1994 till December 2003, the International Classification of Diseases, Ninth Revision, Clinical Modification, was used to code the diseases. On January 2004, the Registry implemented the International Classification of Disease for Oncology, Third Edition (ICD-O-3) to code the cancer cases.

Results

During the last sixteen years, a total of 48,434 neoplasms were registered at SKMCH & RC (of which 2072 were benign and 46,362 malignant). The distributions seen amongst males and females were (49.29% and 50.71%, respectively). About 88.55% tumors were found in adults whereas 11.45% were diagnosed in children. The top three malignancies in all age group and both sexes combined were breast cancer, leukemia, and lip & oral cavity cancer. The top three malignancies amongst adult females were: cancers of the breast, ovary & uterine adnexa, and lip & oral cavity, whereas, in adult males, they were lip & oral cavity, liver & intrahepatic bile ducts and non-Hodgkin’s lymphoma.

In adults, regardless of gender, malignant neoplasm of the breast, lip & oral cavity, and liver and intrahepatic bile ducts, were established as the leading malignancies, whereas, in children, the commonest malignancies were categorized as acute lymphoblastic leukemia (ALL), Hodgkin’s disease, and non-Hodgkin’s lymphoma (NHL).

In the year 2010, a total of 4,107 malignancies were added to the Registry database. Of a total of 4,107 malignant cases, 3,824 (93.11%) were analytical cases, whereas 283 (6.89%) were non analytical cases (Class of case 0 to 2 and 3 to 9 are considered analytical cases and non-analytical cases respectively according to the Facility Oncology Revised Data Standards (FORDS) Revised for 2004). The top three malignancies in all age groups and both sexes combined were breast, liver & intrahepatic bile ducts, and lip & oral cavity cancers. In adult males, liver & intrahepatic bile ducts, lip & oral cavity, and colorectal were the top malignancies whereas in adult females, breast, lip & oral cavity and liver & intrahepatic bile ducts were the leading malignancies. In children, Hodgkin’s lymphoma, acute lymphoblastic leukemia and non-Hodgkin’s lymphoma were the commonest malignancies.

The Registry uses the American Joint Committee on Cancer (AJCC) staging manual for staging all available cancer sites. TNM categorizes cancers in stages 0, 1, 2, 3, 4, and also as unstageable. Amongst 3,824 analytical cases (Class of case 0, 1, 2) , 0.58% cases were staged into stage 0, 12.44% in stage I, 21.56% in stage II, 23.80% in stage III, and 17.29% in stage IV. In 16.55% of the patients, no AJCC stage was defined and 7.79% of the cases were unstageable.

Histological grading was done in 3,824 analytical cases. According to the histology grade, 7.53% presented in Grade I, 22.86% in Grade II, 23.54% in Grade III, 1.54% in Grade IV, and in 44.53% Grade was not determined.

The details of these reports/documents can be viewed by using the following links:

Collective Cancer Registry Report (1994-2010) (PDF file)
Annual Cancer Registry Report (2010) (PDF file)
CRCDM – Confidentiality - June,  2011 (PDF file)

Archived Cancer Registry Reports

(Adobe Acrobat Reader is required to view the reports.)
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Suggested Citation -Cancer Registry and Clinical Data Management (CRCDM) – Shaukat Khanum Memorial Cancer Hospital and Research Center (SKMCH & RC) - (www.shaukatkhanum.org.pk). Report based on cancer cases registered at SKMCH & RC from Dec. 1994-Dec. 2010 and in 2010. Released June, 2011.