The computerized Cancer Registry at SKMCH & RC is a data system designed for collection, management, and analysis of detailed data on patients registered at the Hospital. The Cancer Registry at the Hospital has been functioning since the inauguration of the Hospital in December 1994. Every year the Registry generates cancer statistics according to sex, age, demographic area, topography, morphology, stage, grade etc. From December 1994 till December 2003, the International Classification of Diseases, Ninth Revision, Clinical Modification, was used to code the diseases. On January 2004, the Registry implemented the International Classification of Disease for Oncology, Third Edition (ICD-O-3) to code the cancer cases.
During the last eighteen years, a total of 58,761 neoplasms were registered at SKMCH & RC (of which 2,787 were benign and 55,974 malignant). The distributions seen amongst males and females were (49.07% and 50.93%, respectively). About 89.06% tumors were found in adults whereas 10.94% were diagnosed in children. The top three malignancies in all age group and both sexes combined were breast cancer, leukemia, and lip & oral cavity cancer. The top three malignancies amongst adult females were: cancers of the breast, ovary & uterine adnexa, and lip & oral cavity, whereas, in adult males, they were liver & intrahepatic bile ducts, lip & oral cavity and non-Hodgkin’s lymphoma.
In adults, regardless of gender, malignant neoplasm of the breast, lip & oral cavity, and liver and intrahepatic bile ducts, were established as the leading malignancies, whereas, in children, the commonest malignancies were categorized as acute lymphoblastic leukemia (ALL), Hodgkin’s disease, and non-Hodgkin’s lymphoma (NHL).
In the year 2012, a total of 4,851 malignancies were added to the Registry database. Of a total of 4,851 malignant cases, 4,598 (94.78%) were analytical cases, whereas 253 (5.22%) were non analytical cases (Class of case 0 to 2 and 3 to 9 are considered analytical cases and non-analytical cases respectively according to the Facility Oncology Revised Data Standards (FORDS) Revised for 2004). The top three malignancies in all age groups and both sexes combined were breast, non-Hodgkin’s lymphoma and Hodgkin’s disease. In adult males, prostate, colorectal and non-Hodgkin’s lymphoma were the top malignancies whereas in adult females, breast, ovary, lip & oral cavity and cervix were the leading malignancies. In children, Hodgkin’s lymphoma, acute lymphoblastic leukemia and non-Hodgkin’s lymphoma were the commonest malignancies.
The Registry uses the American Joint Committee on Cancer (AJCC 7th edition) staging manual for staging all available cancer sites. TNM categorizes cancers in stages 0, 1, 2, 3, 4, and also as unstageable. Amongst 4598 analytical cases (Class of case 0, 1, 2) , 0.70% cases were staged into stage 0, 13.11% in stage I, 26.56% in stage II, 22.20% in stage III, and 18.62% in stage IV. In 10.13% of the patients, no AJCC stage was defined and 8.68% of the cases were unstageable.
In histological grading, 6.78% presented in Grade I, 25.53% in Grade II, 23.12% in Grade III, 1.48% in Grade IV, and in 36.54% Grade was not determined. In 6.55% Grade was not applicable.
The details of these reports can be viewed by using the following links:
Collective Cancer Registry Report - Dec. 1994 to Dec. 2012 (PDF file)(Adobe Acrobat Reader is required to view the reports.)
Annual Cancer Registry Report - 2012 (PDF file)
CRCDM – Confidentiality - June, 2012 (PDF file)
Archived Cancer Registry Reports
- Cancer Registry and Clinical Data Management (CRCDM) – Shaukat Khanum Memorial Cancer Hospital and Research Center (SKMCH & RC) - (www.shaukatkhanum.org.pk). Report based on cancer cases registered at SKMCH & RC from Dec. 1994-Dec. 2012 and in 2012. Released June, 2013.